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Alkaloid Chemistry


The Alkaloids, Volume 58

The Alkaloids, Volume 58 Lowest new price: $65.17
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This series is world-renowned as the leading compilation of current reviews of this vast field.
Internationally acclaimed for more than forty years, The Alkaloids: Chemistry and Biology, founded by the late Professor R. H. F. Manske, continues to provide outstanding coverage of the rapidly expanding field of the chemotaxonomy, structure elucidation, synthesis, biosynthesis, and biology of all classes of alkaloids from higher and lower plants, marine organisms, and various terrestrial animals. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids.
This, the 58th volume in the series presents two quite different aspects of alkaloids. The first of the two chapters reviews the substantial progress made on the biotransformations of various classes of alkaloids and examines the enzymes systems involved in this process. Such studies are proving very important in the consideration of how alkaloids can be used in the future as medicinal or biological agents. The second chapter presents a comprehensive review of the known polyamine alkaloids based on their biogenesis and additionally provides overviews of their detailed structural analysis, their synthesis, biosynthesis and biology.

* The 58th volume in this series of essential reference works

* Written by leading experts in the field

* An essential research tool for anyone working with alkaloids in chemistry or biology

Alkaloids (Molecular Methods of Plant Analysis New Series)

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Author: H. F. Linskens

It is refreshing to find a book treating alkaloid analysis with all the latest techniques such as inverse-detected two dimensional NMR, GC/MS, and HPLC associated techniques. There have been many developments in the field of alkaloid analysis since the 1950s, not the least of which are the various powerful spectroscopic methods, which dominate this volume. Included also are the various aspects of tobacco alkaloids and analysis in various situations. The complexities of sampling and analysis in tobacco smoke is explained. Analysis of alkaloids produced by tobacco root cell cultures is included, while genetic and chemical analysis is described for Papaver, a plant of considerable medicinal significance.

Alkaloids (Volume 5)

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This is the fifth volume which will provide comprehensive and authoritative reviews of the chemistry and biological properties of the various classes of alkaloids. The scope of these volumes will include structure elucidation, synthesis, biogenesis, pharmacology, physiology, taxonomy, spectroscopy and x-ray crystallography of alkaloids. Certain chapters will include treatment of several subjects such as structure of elucidation, synthesis and pharmacology, whereas other chapters will treat a single aspect of alkaloids.

Alkaloids, Vol 13 (SPR Alkaloids (RSC))

Alkaloids, Vol 13 (SPR Alkaloids (RSC)) Lowest new price: $433.80
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Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry.

Alkaloids: Chemical and Biological Perspectives 7

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This monograph series provides unprecedented interdisciplinary coverage of research relating to the chemistry and biology of alkaloids - a class of biologically active compounds of more than 10,000 members. Timely, comprehensive and authoritative, the series features chapters on chemical properties and structure elucidation, synthesis, biosynthesis, taxonomy, spectroscopy, pharmacology, and toxicology. These vol- umes will provide valuable information for investigators working in such diverse fields as medical chemistry, natural products chemistry, pharmacology, pharmacognosy, physiology, biochemistry, phytochemistry, plant taxonomy, oncology, forensic science, and medicine. The chapters are written by eminent researchers, all of them acknowledged experts in the field. Subject and organism indexes are included.

Alkaloids: Chemical and Biological Perspectives 8

Alkaloids: Chemical and Biological Perspectives 8 Lowest new price: $49.00
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Alkaloids: Chemical and Biological Perspectives, Vol. 6

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This volume provides comprehensive reviews of the chemistry and biological properties of the various classes of alkaloids. The scope of the volumes in this series includes structure elucidation, synthesis, biogenesis, pharmacology, physiology, taxonomy, spectroscopy and X-ray crystallography of alkaloids. Some chapters include treatment of several subjects such as structure of elucidation, synthesis and pharmacology, whereas other chapters treat a single aspect of alkaloids.

Alkaloids: Chemical and Biological Perspectives, Volume 10

Alkaloids: Chemical and Biological Perspectives, Volume 10 Lowest new price: $209.00
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Volume 10 of this series presents four timely reviews. Chapter 1 provides a fascinating account of the history of alkaloid discovery in Australia beginning with the isolation of the first alkaloid from an Australian plant, the Tasmanian sassafras (Atherosperma moschatum), by Zeyer in 1861. Also included is a comprehensive survey of alkaloid-bearing plants, and a section dealing with detection, estimation, extraction, and work-up procedures for alkaloids.

Chapter 2 provides a comprehensive update to the chapter on "Pyridine and Piperidine Alkaloids" which appeared in volume 3 of this series. The focus of this chapter is on new alkaloids isolated, biosynthesis, and biological properties.

Chapter 3 looks at "3-Alkylpiperidine Alkaloids Isolated from Marine Sponges in the Order Haplosclerida". Studies over the past thirty years have shown that sponges are a rich source of alkaloids. Many of these sponge alkaloids are related to each other by the presence of a 3-alkylpiperidine moiety in their structures and it happens that the sponges that have been reported to contain 3-alkylpiperidine alkaloids are all in the order Haplosclerida.

Chapter 4 reviews &bgr;-carboline and isoquinoline alkaloids which are pharmacologically some of the most significant marine natural products. This chapter treats the isolation, structure elucidation, synthesis, biosynthesis, and pharmacological activity of these alkaloids.

Alkaloids: Chemical and Biological Perspectives, Volume 11, Volume 11

Alkaloids: Chemical and Biological Perspectives, Volume 11, Volume 11 Lowest new price: $202.49
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Volume 11 of this series presents five timely reviews on current research on alkaloids. Chapter 1 by Paul L. Schiff, Jr. is a monumental survey of research that has been carried out over the past decade on the Thalictrum alkaloids. Forty-six new alkaloids are described from fifteen species of the genus Thalictrum, as well as 116 alkaloids of known structure from thirty-six species and subspecies of the genus. The chapter includes discussions of isolation and structure elucidation, analysis, biosynthesis, cell culture, and pharmacology. Also featured are inclusive compilations of botanical sources, alkaloids by alkaloid types, and calculated molecular weights of the Thalictrum alkaloids.

Chapter 2 by Giovanni Appendino provides a fascinating treatment of Taxine, a collective name referring to a mixture of diterpenoid alkaloids from the yew tree (genus: Taxus). Taxine is responsible for the toxic properties of the yew tree that has been documented in historical and fictional literature, from Julius Caesar to Shakespeare, and from Agatha Christie to T.S. Eliot. The chapter treats the history, isolation techniques, structure elucidation, chemistry, and pharmacology of Taxine.

Chapter 3 by Mary D. Menachery surveys the alkaloids of South American Menispermaceae (moonseed family). Many different structural types are included in this family. The alkaloid-bearing plants are woody-vines, shrubs, or small trees. Several of these species possess potent curare activity. The chemistry as well as pharmacology of these alkaloids is summarized.

Chapter 4 by Russell J. Molyneux, Robert J. Nash, and Naoki Asano treats the chemistry and biological activity of the calystegines and related nortropane alkaloids. These polyhydroxylated bicyclic alkaloids represent another class of compounds that inhibit glycosidases, producing profound effects in biological systems by disrupting the essential cellular function of glycoprotein processing.

Chapter 5, a related chapter by Robert J. Nash, Naoki Asano, and Alison A. Watson, reviews polyhydroxylated alkaloids that inhibit glycosidases. Topics covered include distribution, ecological significance and toxicity, isolation, synthesis, and biosynthesis.

Alkaloids: Chemical and Biological Perspectives, Volume 12, Volume 12

Alkaloids: Chemical and Biological Perspectives, Volume 12, Volume 12 Lowest new price: $212.37
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Acronycine, a potent antitumor agent, was discovered in the bark of the small Australian Rutaceous tree, Acronychia baueri Schott. This new work presents a comprehensive survey of the isolation, structure determination, methods of synthesis, and the biological properties of acronycine, as well as an account of natural and synthetic analogues of acronycine, and their biological properties.
Solanum alkaloids were reviewed in 1990 and this book surveys the new developments (isolation procedures, structural elucidation methods) and critically updates earlier reviews. In addition it presents the interesting chemistry and synthesis of cyclopeptide alkaloids. These cyclopeptide alkaloids have been isolated from ascidians, sea hares, and cyanobacteria. Also included are reviews of the use of the functionalized lactam, pyroglutamic acid, as a chiral template for the synthesis of alkaloids. The second review examines the on-line coupling of capillary electrophoresis (CE) and mass spectrometry (MS) for the analysis of alkaloid mixtures. Finally a review of oxygenated analogs of the alkaloid Marcfortine for their potent antiparasitic activity is included at the end of this work.
Each chapter in this volume has been reviewed by at least one expert in the field. Indexes for both subjects and organisms are provided.

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