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Molecular Biology


DNA Repair and Mutagenesis

DNA Repair and Mutagenesis Lowest new price: $50.00
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Author: Errol C. Friedberg

An essential resource for all scientists researching cellular responses to DNA damage. • Introduces important new material reflective of the major changes and developments that have occurred in the field over the last decade. • Discussed the field within a strong historical framework, and all aspects of biological responses to DNA damage are detailed. • Provides information on covering sources and consequences of DNA damage; correcting altered bases in DNA: DNA repair; DNA damage tolerance and mutagenesis; regulatory responses to DNA damage in eukaryotes; and disease states associated with defective biological responses to DNA damage.

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Cells, Aging, and Human Disease

Cells, Aging, and Human Disease Lowest new price: $86.51
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List price: $110.00
Author: Michael B. Fossel

Cells, Aging, and Human Disease is the first book to explore aging all the way from genes to clinical application, analyzing the fundamental cellular changes which underlie human age-related disease. With over 4,000 references, this text explores both the fundamental processes of human aging and the tissue-by-tissue pathology, detailing both breaking research and current state-of-the-art clinical interventions in aging and age-related disease.

Far from merely sharing a common onset late in the lifespan, age-related diseases are linked by fundamental common characteristics at the genetic and cellular levels. Emphasizing human cell mechanisms, the first section presents and analyzes our current knowledege of telomere biology and cell senescence. In superb academic detail, the text brings the reader up to date on telomere maintenance, telomerase dynamics, and current research on cell senescence--and the general model--cell senescence as the central component in human senescence and cancer. For each human malignancy, the chapter reviews and analyzes all available data on telomeres and telomerase, as well as summarizing current work on their clinical application in both diagnosis and cancer therapy.

The second edition, oriented by organs and tissues, explores the actual physiological impact of cell senescence and aging on clinical disease. After a summary of the literature on early aging syndromes--the progerias--the text reviews aging diseases (Alzheimer's dementia, osteoarthritis, atherosclerosis, immune aging, presbyopia, sarcopenia, etc.) in the context of the tissues in which they occur. Each of the ten clinical chapters--skin, cardiovascular system, bone and joints, hematopoetic and immune systems, endocrine, CNS, renal, muscle, GI, and eyes--examines what we know of their pathology, the role of cell sensescence, and medical interventions, both current and potential.

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Protein Stucture and Function (Primers in Biology) (PRIMER IN BIOLOGY)

Protein Stucture and Function (Primers in Biology) (PRIMER IN BIOLOGY) Lowest new price: $41.50
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Author: Gregory A. Petsko
Brand: Brand: Sinauer Associates, Inc.

Published by New Science Press, this text introduces general principles of protein structure, folding, and function, then goes beyond these basics to tackle the conceptual basis of inferring structure and function from genomic sequence. It is the first book in a series, Primers in Biology, employing a modular design in which chapters are divided into topics, each occupying one two-page spread that includes the relevant text, illustrations (in full color), definitions, and references.

The book has five chapters. The first is an introduction to the principles of protein structure and folding, with emphasis on proteins' biophysical properties. The second describes the principles of the main biochemical functions of proteins, namely binding and catalysis, with a short section on the properties of structural proteins. Chapter 3 covers the regulation of protein function, containing concise descriptions of all the regulatory mechanisms that operate on proteins, from pH to phosphorylation, with several sections on protein switches based on nucleotide hydrolysis. Chapter 4 introduces the principles whereby structure and function are deduced from sequence, with illustrative examples. The final chapter addresses how data on protein structure is gathered, interpreted, and presented.

Written for upper-level undergraduates and beginning graduate students, Protein Structure and Function will also be useful for working scientists needing an up-to-date introduction to the field.

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  • Used Book in Good Condition

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DNA Sequencing: Optimizing The Process And Analysis

DNA Sequencing:  Optimizing The Process And Analysis Lowest new price: $36.99
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Author: Jan Kieleczawa

DNA sequencing techniques have evolved rapidly in recent years — largely resulting from the Human Genome Project — but scientists still encounter challenges in sequencing genomes. DNA Sequencing was written to help scientists sequence difficult templates. It is also a practical guide to faster and more efficient routine DNA sequencing.

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Have a Nice DNA (Enjoy Your Cells, 3)

Have a Nice DNA (Enjoy Your Cells, 3) Lowest new price: $7.94
Lowest used price: $27.24
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Author: Fran Balkwill
Brand: Cold Spring Harbor Laboratory Press
Model: FBA-|287250

Enjoy Your Cells is a new series of children's books from the acclaimed creative partnership of scientist/author Fran Balkwill and illustrator Mic Rolph. Once again, they use their unique brand of simple but scientifically accurate commentary and exuberantly colorful graphics to take young readers on an entertaining exploration of the amazing, hidden world of cells, proteins, and DNA. It's over ten years since Fran and Mic invented a new way of getting science across to children. Think what extraordinary advances have been made in biology in that timeand how often those discoveries made headlines. Stem cells, cloning, embryo transfer, emerging infections, vaccine developmentELhere in these books are the basic facts behind the public debates. With these books, children will learn to enjoy their cells and current affairs at the same time. And they're getting information that has been written and reviewed by working scientists, so it's completely correct and up-to-date. Readers aged 7 and up will appreciate the stories' lively language and with help, even younger children will enjoy and learn from the jokes and illustrationsno expert required! This series is a must for all elementary school students and those who care about educating them to be well-informed in a world of increasingly complex health-related and environmental issues.

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Culture of Animal Cells: A Manual of Basic Technique

Culture of Animal Cells: A Manual of Basic Technique Lowest new price: $70.00
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Author: R. Ian Freshney

The most complete resource on the techniques, equipment,principles, and practices of animal cell culture

Since publication of the previous edition of this benchmark text, numerous groundbreaking advances have occurred in stem cell research, cloning, tissue engineering, and in vitro toxicity testing. These and other developments have been incorporated into this fully revised and expanded Fifth Edition of Culture of Animal Cells. In addition, to answer the needs of the exponential increase in newcomers to cell culture, particularly in the biopharmaceutical industry, a completely new chapter on training in cell culture technology has been introduced.

The most complete resource on the techniques, equipment, principles, and practices of animal cell culture, this text offers a complete background related to growth of animal cells in culture. Beginning with laboratory design, safety, validation and bioethics, then continuing with preparation of media, primary culture and cell lines, through to characterization and authentication, contamination, specialized techniques, and troubleshooting, the coverage includes:
* An all-new section of training exercises, separated into basic, intermediate, and advanced procedures, cross-referenced to the relevant protocols
* New coverage of stem cells, bioethics, validation, cloning, cell signaling, in vitro toxicity testing, and tissue engineering
* An expanded full-color atlas section, with images of primary culture, cell lines, subculture, differentiation, cancer cells and transformation, three-dimensional culture, contamination, and specialized equipment
* Enhanced treatment of troubleshooting, with full cross-referencing to the relevant protocols and sections of text
* Fully updated references
* The clearest, most consistent presentation of step-by-step protocols available
* Numerous diagrams, photographs, tables, and charts
* Detailed and up-to-date information on reagent preparation and sourcing of materials and equipment, including a fully updated list of suppliers and other resources with Web sites

Indispensable for clinical and biopharmaceutical researchers and scientists, students, trainees, and technicians, this landmark text presents the most accessible and comprehensive introduction available to the culture and experimental manipulation of animal cells.

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Molecular Genetics of Bacteria, Third Edition (Snyder, Molecular Genetics of Bacteria)

Molecular Genetics of Bacteria, Third Edition (Snyder, Molecular Genetics of Bacteria) Lowest new price: $25.23
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Author: Larry Snyder
Brand: Brand: ASM Press

This landmark volume provides the single most comprehensive and authoritative textbook on bacterial molecular genetics. Perfect for advanced undergraduate and graduate-level courses, the text presents the latest research on the subject in a clearly written and well-illustrated style. It provides descriptive background information, detailed experimental methods, examples of genetic analyses, and advanced material relevant to current applications of molecular genetics. While providing a deep understanding of bacterial molecular genetics, the material is integrated with biochemical, genomic, and structural information to broaden understanding. The approach centers on the most-studied bacteria, Escherichia coli and Bacillus subtilis. In addition, examples from other bacteria with medical, ecological, or biotechnological significance are covered throughout the text. The material in each chapter has been substantially revised and rewritten and reflects exciting developments in the field of bacterial molecular genetics and its relationship to other fields, including genetics, biotechnology, and bioengineering. Molecular Genetics of Bacteria, 3rd Edition is organized like the two previous editions. Each chapter contains a summary of main points, descriptions of significant experiments, a set of discussion questions and a problem set (with answers to both at the back of the book), and a list of suggested readings-all updated to reflect the most recent advances in the field. Additionally, text boxes present intriguing information on each topic without interrupting the continuity of the text. This third edition is invaluable to anyone working in the fields of microbiology, genetics, biochemistry, bioengineering, medicine, molecular biology, and biotechnology. It is also essential reading for scientists in all fields of biology, many of whom depend upon the concepts and techniques covered in this book. New in the Third Edition* Features completely revised and updated material, incorporating the most recent advances in the field since publication of the second edition in 2002* Introduces over 100 brand-new illustrations* Offers a revised and expanded glossary containing approximately 1,000 entries Key Features and Benefits* Each chapter includes a concise end-of-chapter summary of the material covered* Incorporates text boxes that introduce readers to exciting developments and related topics of interest* Provides thought questions, problems, and suggested reading lists at the conclusion of each chapter that test student comprehension and encourage further research* Written by only two authors, both of whom are specialists in the field and who have significant experience teaching the subject of bacterial molecular genetics* Integrates biochemical, genomic, and structural information that broadens the knowledge obtained from molecular genetics* Focuses on the most widely studied bacteria, Escherichia coli and Bacillus subtilis, but incorporates many examples from other bacteria of medical, ecological, and biotechnological importance

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From a to alpha: Yeast as a Model for Cellular Differentiation

From a to alpha: Yeast as a Model for Cellular Differentiation Lowest new price: $30.00
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Author: Hiten D Madhani

Related Titles from the Publisher Binding and Kinetics for Molecular Biologists; Methods in Yeast Genetics: A Cold Spring Harbor Laboratory Course Manual, 2005 Edition; Landmark Papers in Yeast Biology


Biochemical Oscillations and Cellular Rhythms: The Molecular Bases of Periodic and Chaotic Behaviour

Biochemical Oscillations and Cellular Rhythms: The Molecular Bases of Periodic and Chaotic Behaviour Lowest new price: $77.81
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Author: Albert Goldbeter
Brand: Brand: Cambridge University Press

This book addresses the molecular bases of some of the most important biochemical rhythms known at the cellular level. The approach rests on the analysis of theoretical models closely related to experimental observations. Among the main rhythms considered are glycolytic oscillations observed in yeast and muscle, oscillations of cyclic AMP in Dictyostelium amoebae, intracellular calcium oscillation observed in a variety of cell types, the mitotic oscillator that drives the cell division cycle in eukaryotes, pulsatile hormone signaling, and circadian rhythms in Drosophila. This book will be of interest to life scientists such as biochemists, cell biologists, chronobiologists, medical scientists and pharmacologists. In addition, it will appeal to scientists studying nonlinear phenomena, including oscillations and chaos, in chemistry, physics, mathematics and theoretical biology.

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  • Used Book in Good Condition

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Physical Biology of the Cell

Physical Biology of the Cell Lowest new price: $96.35
Lowest used price: $42.93
List price: $158.00
Author: Rob Phillips
Brand: Brand: Garland Science

Physical Biology of the Cell is a biophysics textbook that explores how the basic tools and insights of physics and mathematics can illuminate the study of molecular and cell biology. Drawing on key examples and seminal experiments from cell biology, the book demonstrates how quantitative models can help refine our understanding of existing biological data and also be used to make useful predictions. The book blends traditional models in cell biology with the quantitative approach typical in physics, in order to introduce the reader to both the possibilities and boundaries of the emerging field of physical biology. While teaching physical model building in cell biology through a practical, case-study approach, the text explores how quantitative modeling can be used to build a more profound, intuitive understanding of cell biology.

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